The Journal of Neuroscience just published a new study that is particularly interesting in light of recent reports that marijuana may effectively substitute for abuse of more dangerous drugs.

In the new study, rats were taught to self-administer heroin and conditioned to associate that behavior with a light that flashed on above the lever that dispensed the heroin. At various stages in the procedure, some of the rats were treated with cannabidiol (CBD), a cannabinoid that doesn’t make you high, but which has a number of really interesting properties. [Read more →]

One thing that drives me crazy is the tendency of the media and others to refer to THC as “the active ingredient” in marijuana. While THC is indeed responsible for marijuana’s “high,” it is one of about 80 unique compounds, called cannabinoids, that are not seen in any other plant. Many of these have interesting, potentially significant, medical applications, and are not psychoactive.

Anyone who wants to learn about these other cannabinoids should check out this recent review published in the journal Trends in Pharmacological Sciences. [Read more →]