There is evidence that marijuana may work synergistically with opioid pain drugs, allowing equal or better relief with reduced doses of narcotics and reduced development of tolerance to the drugs. But most of this evidence comes from animal studies, so data from human clinical trials is urgently needed.
Dr. Donald Abrams of the University of California, San Francisco, is doing just such a study right now and needs volunteers who are suffering from chronic pain and currently taking OxyContin or MS Contin. Compensation and assistance with transportation to San Francisco are available. If you or anyone you know might be eligible to participate, please check out the details here and consider joining this important effort.